328 Risks Factors for Developing Neonatal Parenteral Nutrition- Associated Cholestasis
نویسندگان
چکیده
منابع مشابه
Parenteral nutrition associated cholestasis
Parenteral nutrition (PN) is life saving for many preterm infants and other neonates with severe illness, but prolonged use of PN can lead to intrahepatic cholestasis, referred to as parenteral nutrition–associated cholestasis (PNAC). It is defined as direct bilirubin greater than 2.0 mg/dL persistent for at least 2 consecutive tests duringthe administration of PN, not associated with other kno...
متن کاملEffect of S-adenosylmethionine on total parenteral nutrition-associated cholestasis
Methods: Twenty-four newborn rabbits were randomly divided into 3 groups: normal control group receiving breast milk, TPN group receiving TPN at a dose of 200 kcal/kg per day, and SAMe group receiving TPN plus SAMe at an intravenous dose of 100 mg/kg per day. Blood and liver samples were collected one week later. The levels of serum bile acid, alanine aminotransferase (ALT), alkaline phosphatas...
متن کاملTotal Parenteral Nutrition – Associated Cholestasis (TPNAC) in Newborns
Pediatrics Gastroenterologist & Master in Clinical Nutrition, Chief of Pediatrics Gastroenterology, Hepatology and Nutrition Department, Clínica del Niño PREVIANDES & Professor of Pediatric Gastroenterology & Pediatric Department Universidad El Bosque, Master in Clinical Nutrition and Professor of Pediatric Gastroenterology & Pediatric Department Universidad El Bosque, Pediatrician visitors Cor...
متن کاملNeonatal and pediatric parenteral nutrition.
Parenteral nutrition is one of the most important therapeutic modalities invented in the last several decades. Since its introduction in the 1960s, this modality has saved thousands of lives by providing nutrients parenterally to sustain growth in premature neonates with severe intestinal immaturity and other pediatric patients with intestinal failure, such as a gastrointestinal fistula or shor...
متن کاملAggressive nutrition in extremely low birth weight infants: impact on parenteral nutrition associated cholestasis and growth
BACKGROUND Parenteral nutrition associated cholestasis (PNAC) is a frequently observed pathology in extremely low birth weight (ELBW) infants. Its pathogenesis is determined by the composition and duration of parenteral nutrition (PN) as well as the tolerance of enteral feeds (EF). "Aggressive" nutrition is increasingly used in ELBW infants to improve postnatal growth. Little is known about the...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2010
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-201011001-00328